13 Haziran 2012 Çarşamba

Leptin Helps Regulate Hormones In Women With Low Body Fat

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All you diet and exercise fanatics out there may not be doing your fertility any favors. Although these are things that we typically think as good, too much of a good thing may sabotage your efforts to get pregnant. Losing too much body fat can affect your levels of "leptin" which starts a chain hormonal reaction. This article explains more:

www.sciencedaily.com

From the article:

Now, a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) offers the first definitive proof that a lack of leptin contributes to hypothalamic amenorrhea (HA) and that treatment with a synthetic form of the hormone can restore fertility and reduce the risk of bone fractures in this group of patients. The findings are reported on-line this week in the Proceedings of the National Academy of Sciences (PNAS).

"This condition accounts for over 30 percent of all cases of amenorrhea in women of reproductive age, and is an important problem for which we didn't have a good solution," explains senior author Christos Mantzoros, MD, Dsc, Director of the Human Nutrition Unit at BIDMC and Professor of Medicine at Harvard Medical School.

"Our findings now prove beyond any doubt that leptin is the missing link in women with significantly diminished body fat, and that this, in turn, results in numerous hormonal abnormalities." Without leptin, he explains, menstrual periods cease, the body becomes chronically energy-deprived and women experience bone loss and an increased risk of bone fractures.

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